In both research, after the administration of OPANA ER, the Cmax was improved by somewhere around 50% in fed topics compared to fasted subjects. The same boost in Cmax was also noticed with oxymorphone Remedy.?????? ??? ?????? ??????? ?? ?????? ?????? ???????? (??? ???? ?????? ????? ??? ??????? ?? ???? ??????? ?? ??????? ?? ???????.?? ?????? ??????